BIONET Therapeutics: Leading the Future of Regenerative Medicine with Stem Cell and Exosome Technology BIONET Therapeutics is at the forefront of regenerative medicine, leveraging advanced stem cell and exosome technologies to drive innovation and transform industries. With a robust technological foundation and a team of experts, we have developed the Exosome Foundry business model, which offers end-to-end exosome solutions—from research and development to large-scale production and a diverse portfolio, bringing groundbreaking advancements to aesthetic medicine. Core Capabilities and Key Innovations 1. Cutting-Edge R&D and Technology o 25 years accumulated stem cell banks: BIONET has established specialized Cell Banks for stem cell storage, supporting the scalable manufacturing of high-quality exosomes. Our state-of-the-art infrastructure ensures a stable and continuous supply of products for global demand. o AI-Driven Innovation: We employ artificial intelligence (AI) and advanced scientific computing to analyze miRNA and proteins in exosomes. These insights enhance immune modulation, promote tissue regeneration, and improve cell repair, advancing aesthetic applications. 2. Product Portfolio and Services o Exosome-Based Skincare and Hair Care: Our innovative exosome-based products cater to the rapidly growing beauty and wellness markets in Asia and beyond. These include cutting-edge skincare solutions that target anti-aging, skin rejuvenation, and hydration, providing noticeable improvements in skin texture and elasticity. Our hair care products are designed to promote hair growth, improve scalp health, and address hair thinning, all using the regenerative power of exosomes to stimulate and repair damaged tissues. These advanced solutions represent the future of cosmetic and aesthetic medicine, providing non-invasive, highly effective treatments for skin and hair health. o CRDMO Services: BIONET offers Contract Research, Development, and Manufacturing Organization (CRDMO) services to industries including biotechnology, pharmaceuticals, skincare, and veterinary sectors. Our flexible services are designed to meet the unique needs of each industry partner. 3. Strategic Market Growth o Expanding Footprint in Aesthetic Medicine: In 2024, BIONET successfully entered the top 20 aesthetic medical institutions in Taiwan, showcasing our rapid market penetration and acceptance in the global aesthetics sector. o Global Market Expansion: BIONET is actively expanding its presence in North America, Europe, South America, Asia, and Oceania, with a focus on Korea and Thailand. We are dedicated to strengthening partnerships with local industries and accelerating the industrialization of regenerative medicine through our versatile distribution channels. By combining cutting-edge innovation with local expertise, BIONET is uniquely positioned to lead the next wave of industry transformation in Asia and globally.

Product 1. ANIKINE Aesthetic Skincare Series for use and sale in the aesthetic medicine clinics  (Skin) Stem-repairing complex  (Skin) Stem-care complex  (Hair) Stem-hair solutions Active ingredients: Umbilical cord mesenchymal stem cells-derived exosomes with specific secret ingredients for skin and hair Application: Topical application in combination with clinical aesthetic treatment sessions to enhance skin repair, anti-aging, and scalp care. 2. MetaExosome Home Skincare Series  (Skin) Exosome sensitive skin care  (Skin) Stem care complex  (Hair) Exosome hair care Active ingredients: Umbilical cord mesenchymal stem cells-derived exosomes Application: Topical application for skin and hair care at home 3. EXOVIA / ExoCake Umbilical cord stem cell derived exosomes (EXOVIA: liquid; ExoCake: dry) to promote collagen synthesis, improve skin condition, regulate the immune system, and strengthen hair growth. The products have been independently certified for safety and effectiveness by a reputable third-party testing organization. Active ingredients: Umbilical cord mesenchymal stem cells-derived exosomes Application: Topical application; can be combined with clinical treatment devices to effectively promote skin and hair regeneration and repair. BIONET Therapeutics have obtained the Certificate of Free Sale (CFS) of ExoCake and EXOVIA in Malaysia. ExoCake and EXOVIA are also registered in the TFDA website. 4. Exosome Raw Materials production Sourced from human, animal, and plant origins, exosome raw materials are suitable for cosmetics, medical devices, and pharmaceutical development, driving the diverse applications of exosome technology Service 5. PRE treatment program Customized, autologous platelet-rich exosomes rich in high concentration growth factors (PDGF, IGF-1, Angiogenin) to smooth wrinkles, restore youthful radiance, and provide comprehensive scalp care to effectively boosting hair volume (density and thickness).